Albion research
Retatrutide 10mg
Retatrutide 10mg
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Retatrutide – Triple Hormone Receptor Agonist.
Retatrutide is a peptide-based therapeutic designed as a triple agonist of the GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors. This unique mechanism sets it apart from current single- or dual-agonist therapies, offering a more comprehensive approach to managing obesity and metabolic disorders.
Mechanism of Action
• GLP-1 receptor activation: Enhances satiety, slows gastric emptying, and reduces appetite.
• GIP receptor activation: Improves insulin sensitivity and amplifies postprandial insulin secretion.
• Glucagon receptor activation: Increases energy expenditure and promotes fat metabolism.
By combining these pathways, Retatrutide addresses both caloric intake and energy utilization, creating a synergistic effect for weight reduction and metabolic control.
Potential Benefits
• Significant Weight Reduction: Early clinical studies have shown substantial and sustained body weight loss in participants, surpassing outcomes of current GLP-1-based therapies.
• Improved Glycemic Control: Enhances insulin secretion and sensitivity, leading to better regulation of blood glucose levels.
• Metabolic Health: Positive effects on lipid metabolism, liver fat reduction, and markers of cardiometabolic health.
• Energy Balance Optimization: Promotes fat oxidation and prevents compensatory decreases in energy expenditure often observed with weight loss.
